Checler, F: search on Z-Library

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1

P4-317 Gamma-secretase inhibitors: a critical evaluation of their potential therapeutic use in Alzheimer disease

Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

2

Chronic fornix deep brain stimulation in a transgenic Alzheimer’s rat model reduces amyloid burden, inflammation, and neuronal loss

Leplus, Aurelie, Lauritzen, Inger, Melon, Christophe, Kerkerian-Le Goff, Lydia, Fontaine, Denys, Checler, Frederic

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2018

Language:

english

File:

PDF, 17.83 MB

english, 2018

3

Influence of Region-Specific Alterations of Neuropeptidase Content on the Catabolic Fates of Neuropeptides in Alzheimer's Disease

Carole Ichai, Nathalie Chevallier, Pia Delaere, Pascal Dournaud, Jacques Epelbaum, Jean-Jacques Hauw, Jean-Pierre Vincent, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

4

Neuropeptidases in cortical areas and in the cerebellum in Alzheimer's disease: Region-specific alterations lead to modified catabolic fate of somatostatin(1–14)

C. Ichai, N. Chevallier, P. Delaere, P. Dournaud, J. Epelbaum, J.J. Hauw, J.P. Vincent, F. Checler

Journal:

Year:

1993

Language:

english

File:

PDF, 143 KB

english, 1993

5

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation

Goiran, Thomas, Duplan, Eric, Rouland, Lila, el Manaa, Wejdane, Lauritzen, Inger, Dunys, Julie, You, Han, Checler, Frédéric, Alves da Costa, Cristine

Journal:

Cell Death & Differentiation

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

6

Neurotensin-Metabolizing Peptidases in Rat Fundus Plasma Membranes

Frédéric Checler, Hélène Barelli, Chiu-Yin Kwan, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 578 KB

english, 1987

7

Presenilin-directed inhibitors of γ-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells

Cristine Alves da Costa, Erwan Ayral, Jean-François Hernandez, Peter St George-Hyslop, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 215 KB

english, 2004

8

P1-209 APH-1 and PEN-2: a study on their proteolysis

Julie Dunys, Peter St George-Hyslop, Cristine Alves da Costa, Frédéric Checler

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 154 KB

english, 2004

9

Beta- and gamma-secretases: Could they be seen as therapeutic molecular targets

Journal:

European Neuropsychopharmacology

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

10

Gamma-secretase as a molecular target: Design, characterization and properties of new non peptidic inhibitors

F. Checler, A. Petit

Journal:

European Neuropsychopharmacology

Year:

2002

Language:

english

File:

PDF, 261 KB

english, 2002

11

BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease

Linda Chami, Frédéric Checler

Journal:

Molecular Neurodegeneration

Year:

2012

Language:

english

File:

PDF, 503 KB

english, 2012

12

Characterization of a new ADAM as a key player of the APP metabolism

Letronne, Florent, Laumet, Geoffroy, Demiautte, Florie, Colin, Morvane, Ayral, Anne-Marie, Hot, David, Hansmannel, Franck, Mounier, Anais, Berr, Claudine, Huot, Ludovic, Checler, Frederic, Pasquier, F

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

13

Experimental stroke: neurolysin back on stage

Checler, Frédéric

Journal:

Journal of Neurochemistry

Year:

2014

Language:

english

File:

PDF, 235 KB

english, 2014

14

Caspase-3-derived C-terminal Product of Synphilin-1 Displays Antiapoptotic Function via Modulation of the p53-dependent Cell Death Pathway

Giaime, E., Sunyach, C., Herrant, M., Grosso, S., Auberger, P., McLean, P. J., Checler, F., da Costa, C. A.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 879 KB

english, 2006

15

Insulin stimulation of amino acid transport in primary cultured rat hepatocytes varies in direct proportion to insulin binding

Jacqueline Dolais-Kitabgi, Frédéric Checler, Jean-François Rey, Odette Morin, Pierre Freychet

Journal:

Year:

1981

Language:

english

File:

PDF, 320 KB

english, 1981

16

Loss of high affinity neurotensin receptors in substantia nigra from parkinsonian subjects

Jean-Louis Sadoul, Frédéric Chécler, Patrick Kitabgi, William Rostène, France Javoy-Agid, Jean-Pierre Vincent

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 1.20 MB

english, 1984

17

694 Development of immunological tools to identify the nature of Aβs in the various lesions observed in Alzheimer's disease

H. Barelli, A. Lebeau, O. Pasquier, J. Vizzavona, P. Delaere, J.P. Vincent, J. Martinez, F. Checler

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 297 KB

english, 1996

18

[TRP11]-Neurotensin and xenopsin discriminate between rat and guinea-pig neurotensin receptors

Frédéric Checler, Catherine Labbé, Claude Granier, Jurphass van Rietschoten, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Year:

1982

Language:

english

File:

PDF, 352 KB

english, 1982

19

Presenilins: Multifunctional Proteins Involved in Alzheimer's Disease Pathology

Checler, Frederic

Journal:

Year:

1999

Language:

english

File:

PDF, 165 KB

english, 1999

20

The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

Hofman, Paul, Ayache, Nicholas, Barbry, Pascal, Barlaud, Michel, Bel, Audrey, Blancou, Philippe, Checler, Frédéric, Chevillard, Sylvie, Cristofari, Gael, Demory, Mathilde, Esnault, Vincent, Falandry,

Journal:

Year:

2019

Language:

english

File:

PDF, 1.44 MB

english, 2019

21

10.1038/8438

Tabira, Takeshi, Chui, De-Hua, Tanahashi, Hiroshi, Ozawa, Kazuharu, Ikeda, Sachiya, Checler, Frédéric, Ueda, Otoya, Suzuki, Hiroshi, Araki, Wataru, Inoue, Haruhisa, Shirotani, Keiro, Takahashi, Keikic

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 994 KB

english, 1999

22

Peripheral inactivation of neurotensin : Isolation and characterization of a metallopeptidase from rat ileum

Hélène BARELLI, Jean-Pierre VINCENT, Frédéric CHECLER

Journal:

Year:

1988

Language:

english

File:

PDF, 1019 KB

english, 1988

23

Le mystère préséniline. La recherche vainqueur par KO ?

Frédéric Checler

Journal:

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie

Year:

1999

Language:

french

File:

PDF, 1.26 MB

french, 1999

24

Role of endopeptidase 3.4.24.16 in the catabolism of neurotensin, in vivo, in the vascularly perfused dog ileum

H. Barelli, J.E.T. Fox-Threlkeld, V. Dive, E.E. Daniel, J.P. Vincent, F. Checler

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

25

Differential catabolic fate of neuromedin N and neurotensin in the canine intestinal mucosa

Hélène Barelli, Y.K. Mao, B. Vincent, E.E. Daniel, J.P. Vincent, F. Checler

Journal:

Year:

1993

Language:

english

File:

PDF, 775 KB

english, 1993

26

C4 L’aminopeptidase A contribue à la dégradation N-terminale du peptide amyloïde et en module la fonction

Amoyel, A., Robert, P., Fournié-Zaluski, M.-C., Roques, B., Sévalle, J., Checler, F.

Journal:

Revue Neurologique

Year:

2009

Language:

french

File:

PDF, 118 KB

french, 2009

27

Catabolism of neurotensin by neural (neuroblastoma clone N1E115) and extraneural (HT29) cell lines

Checler, Frédéric, Amar, Shimon, Kitabgi, Patrick, Vincent, Jean-Pierre

Journal:

Year:

1986

Language:

english

File:

PDF, 710 KB

english, 1986

28

6-Hydroxydopamine but Not 1-Methyl-4-phenylpyridinium Abolishes -Synuclein Anti-apoptotic Phenotype by Inhibiting Its Proteasomal Degradation and by Promoting Its Aggregation

da Costa, C. A., Dunys, J., Brau, F., Wilk, S., Cappai, R., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

29

Editorial [ Production and Fate of Amyloid Peptides: Recent Advances and Perspectives ]

Checler, Frederic

Journal:

Current Alzheimer Research

Year:

2008

Language:

english

File:

PDF, 163 KB

english, 2008

30

Cholinesterases Display Genuine Arylacylamidase Activity but Are Totally Devoid of Intrinsic Peptidase Activities

Frédéric Checler, Jacques Grassi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 773 KB

english, 1994

31

Processing of the β-Amyloid Precursor Protein and Its Regulation in Alzheimer's Disease

Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.49 MB

english, 1995

32

Phosphorus-containing peptides as mixed inhibitors of endopeptidase 3.4.24.15 and 3.4.24.16: effect on neurotensin degradation in vitro and in vivo

Bruno Vincent, Vincent Dive, Athanasios Yiotakis, Claire Smadja, Raphaël Maldonado, Jean-Pierre Vincent, * Frederic Checler

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.74 MB

english, 1995

33

O4-03-08 Role of nicastrin in programmed cell death

Raphaelle Pardossi-Piquard, Gang Yu, Peter St George-Hyslop, Christophe Bourdon, Cristine Alves da Costa, Frédéric Checler

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

34

Lack of effect of Presenilin 1, βAPP and their Alzheimer's disease-related mutated forms on Xenopus oocytes membrane currents

Pascale Dauch, Guy Champigny, Jean-Ehrland Ricci, Frédéric Checler

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 108 KB

english, 1997

35

Molecular Dysfunctions of Mitochondria-Associated Membranes (MAMs) in Alzheimerâs Disease

Eysert, Fanny, Kinoshita, Paula Fernanda, Mary, Arnaud, Vaillant-Beuchot, Loan, Checler, FrÃ©dÃ©ric, Chami, Mounia

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 680 KB

2020

36

Specific inhibition of endopeptidase 24.16 by dipeptides

Pascale DAUCH, Jean-Pierre VINCENT, Frédéric CHECLER

Journal:

Year:

1991

Language:

english

File:

PDF, 797 KB

english, 1991

37

Neuropeptide Specificity and Inhibition of Recombinant Isoforms of the Endopeptidase 3.4.24.16 Family: Comparison with the Related Recombinant Endopeptidase 3.4.24.15

Vanessa Rioli, Akira Kato, Fernanda C.V. Portaro, Gabriela K. Cury, Kai te Kaat, Bruno Vincent, Frederic Checler, Antonio C.M. Camargo, Marc J. Glucksman, James L. Roberts, Shigehisa Hirose, Emer S. F

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

38

Regulation of cyclic GMP levels by neurotensin in neuroblastoma clone N1E115

Shimon Amar, Jean Mazella, Frederic Checler, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 499 KB

english, 1985

39

Intraneuronal Aβ42 Accumulation in Human Brain

Gunnar K. Gouras, Julia Tsai, Jan Naslund, Bruno Vincent, Mark Edgar, Frederic Checler, Jeffrey P. Greenfield, Vahram Haroutunian, Joseph D. Buxbaum, Huaxi Xu, Paul Greengard, Norman R. Relkin

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 1.06 MB

english, 2000

40

Further characterization of a neurotensin-degrading neutral metalloendopeptidase from rat brain

Barelli, Hélène, Girard, Fernand, St. Pierrr, Serge, Kitabgi, Patrick, Vincent, Jean-Pierre, Checler, Frédéric

Journal:

Neurochemistry International

Year:

1988

Language:

english

File:

PDF, 681 KB

english, 1988

41

Development of Highly Potent and Selective Phosphinic Peptide Inhibitors of Zinc Endopeptidase 24-15 Using Combinatorial Chemistry

Jiracek, J., Yiotakis, A., Vincent, B., Lecoq, A., Nicolaou, A., Checler, F., Dive, V.

Journal:

Journal of Biological Chemistry

Year:

1995

Language:

english

File:

PDF, 162 KB

english, 1995

42

Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimerâs Disease

Chami, Mounia, Checler, FrÃ©dÃ©ric

Journal:

Year:

2020

File:

PDF, 1.63 MB

2020

43

JLK isocoumarin inhibitors: Selective γ-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo

A. Petit, A. Pasini, C. Alves da Costa, E. Ayral, J.F. Hernandez, C. Dumanchin-Njock, C.J. Phiel, P. Marambaud, S. Wilk, M. Farzan, P. Fulcrand, J. Martinez, D. Andrau, F. Checler

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

44

Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies

E. Paitel, C. Alves da Costa, D. Vilette, J. Grassi, F. Checler

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 301 KB

english, 2002

45

Peptidasic Activities Associated with Acetylcholinesterase Are Due to Contaminating Enzymes

Frédéric Checler, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 479 KB

english, 1989

46

Effect of a novel selective and potent phosphinic peptide inhibitor of endopeptidase 3.4.24.16 on neurotensin-induced analgesia and neuronal inactivation

Bruno Vincent, Jirì Jiracek, Florence Noble, Mart Loog, Bernard Roques, Vincent Dive, Jean-Pierre Vincent, Frédéric Checler

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

47

Immunohistochemical Analysis of Cerebral Cortical and Vascular Lesions in the Primate Microcebus murinus Reveal Distinct Amyloid β1–42 and β1–40 Immunoreactivity Profiles

Nadine Mestre-Francés, Emeline Keller, Alphonse Calenda, Hélène Barelli, Frédéric Checler, Noëlle Bons

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 236 KB

english, 2000

48

Human amyloid-β causes changes in the levels of endothelial protein kinase C and its α isoform in vitro

Magdolna Pakaski, Lajos Balaspiri, Frederic Checler, Peter Kasa

Journal:

Neurochemistry International

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

49

DEGRADATION OF NEUROTENSIN BY BRAIN SYNAPTIC MEMBRANES

Frédéric Checler, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Annals of the New York Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 135 KB

english, 1982

50

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

Dolores Del Prete,Frédéric Checler,Mounia Chami

Journal:

Molecular Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 871 KB

english, 2014

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